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In patients with Graves disease or hypothyroidism requiring levothyroxine, significant GLP-1RA-induced weight loss may alter thyroid hormone pharmacokinetics and necessitate medication dose adjustments [63]
For people living with rare diseases, these gaps can have serious and lasting consequences
Clinical trial data from the SUSTAIN and STEP programs indicate that nausea, the most frequently reported side effect, generally improves within 46 weeks for most patients as tolerance develops
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