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The story of smoking in the United States is usually presented as a struggle between heroic scientists and activists on the one hand, fighting to get the truth out to the public, and mendacious tobacco industry executives on the other, manipulating members of Congress Milov provides a more interesting and complicated account

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Cigarette smoking significantly affects several drug metabolizing enzymes and transporters, in addition to the well-known effects on cytochrome P450 (especially the CYP1A2 isoform)