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By including all English-language studies on muscle mass loss during GLP-1RA therapy in T2D and obesity from major scientific databases and clinical trial registries, this narrative review synthesizes the current knowledge on the epidemiology and mechanisms of muscle loss in diabetes and obesity, with a focus on the impact of GLP-1RAs therapy

However, there may be unappreciated benefits of this combination of therapies

GLP-1 research tablet provides 25 x 7mg tablets of GLP-1 receptor agonist studied in preclinical models for incretin-pathway signaling, metabolic regulation, and energy-balance pathways

In this Review, the authors discuss the potential effects of GLP-1 receptor agonists on the incidence, disease activity and progression of various forms of arthritis, as well as practical considerations for their use in this context.