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For Wegovy, NICE guidance (TA875) recommends discontinuation if patients do not achieve at least 5% weight loss after 6 months at the maintenance dose, and NHS treatment is typically limited to a maximum of 2 years

Forzet is classified as a medical food intended for the dietary management of muscle loss associated with weight loss therapies under physician supervision

Patients with certain genetic profiles may experience faster satiety, better glucose response, or greater weight loss acceleration

Moreover, in the AMPLITUDE-O, HARMONY OUTCOMES and SUSTAIN-6 trials [50,56,59], there were significant reductions in the expanded composite outcome, defined as hospitalisations for unstable angina and urgent coronary revascularisations