how does a glp 1 agonist work The Ultimate Guide to GLP-1: Basics, Benefits, and More GLP-1 | Summary

In SUSTAIN 3, SUSTAIN 7 and SUSTAIN 10, the GLP-1RAs semaglutide reduced HbA1c by up to 1.8%, achieved the glycemic control target of HbA1c in 80% of the intervention group, and reduced BW by up to 6.5 kg, outcomes which were superior to liraglutide, exenatide and dulaglutide [28-30]

p = 0.02) (Wiberg et al., 2018)

In a study with eight poorly controlled T2DM patients who received a liquid meal via a nasogastric tube and exogenous infusion of GLP-1 to achieve plasma levels of about 70 pM, gastric volume remained constant over 2 hours, and plasma glucose returned to normal fasting values within 3 4 hours (152)

Among them, anti-obesity drugs have high compliance rates and cause noticeable short-term effects in reducing obese levels