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When used as part of CagriSema, the dosing schedule looked like this in trials: Weeks 04: 0.25 mg cagrilintide + 0.25 mg semaglutide Weeks 48: 0.5 mg + 0.5 mg Weeks 812: 1 mg + 1 mg Weeks 1216: 1.7 mg + 1.7 mg Week 16 onward: 2.4 mg + 2.4 mg (full maintenance dose) Until the medication is approved and prescribing information is finalized, any dosing decisions would only happen through participation in a clinical trial or, eventually, under the guidance of a healthcare provider

Pulya, S

If you are taking both a thyroid tablet and your daily semaglutide pill, they can interfere with one another

however, it is still not clear whether this effect was mediated by modulation of sympathetic traffic (Matsumura et al., 2002