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Patients with diabetes who received semaglutide had a higher long-term risk of nonarteritic anterior ischemic optic neuropathy compared with matched patients who received nonglucagon-like peptide-1 receptor agonist antidiabetic medications, according to a retrospective cohort study published in JAMA Ophthalmology

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While TED is most frequently associated with Graves disease (an autoimmune thyroid disorder), it can also occur in people with hypothyroidism or even normal thyroid function

They are not inevitable or irreversible, but they do warrant attention rather than being treated as an acceptable side effect to push through