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One year of sitagliptin treatment protects against islet amyloid-associated beta-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice Am J Physiol Endocrinol Metab 305 4: E475-84

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Although peripheral AC levels may not directly reflect brain-specific alterations, their role in systemic energy balance suggests an impact on central processes like mood regulation [18]

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