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The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

In Arabidopsis, SIR is encoded by a single, essential gene and is described as a bottleneck in the sulfate assimilation pathway ( SIR expression is rapidly upregulated in Arabidopsis and tomato in response to higher sulfite content, and accordingly SIR activity increases (Yarmolinsky et al., 2013)

Any consideration of combination pharmacotherapy should involve shared decision-making, thorough discussion of risks and benefits, and close clinical follow-up

The NADPH oxidase isoform NOX1 transiently produces a burst of superoxide in response to growth factor (e.g