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MPTP and Parkinson MPTP is a widely used neurotoxicant, known for the induction of Parkinson-like symptoms such as bradikinesia, movement disorders, -synuclein bodies, mitochondrial abnormalities, sustained inflammation in the substantia nigra and activation of the microglia [6,10,15, 79-80]

[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Bayindir Z.S., Yuksel N

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Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca2+ homeostasis