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Nanoparticles functionalized with neuron-specific ligands can promote preferential neuronal uptake and increase drug accumulation at synaptic sites while minimizing systemic exposure

Moreover, the largest clinical trials included in the meta-analysisand, in consequence, those with more power in the analysisused vitamins E and C, i.e., supplements without proven beneficial effects

10.1016/j.devcel.2010.05.008 Dev

Discussion In this study, we demonstrate that co-treatment with 3-BP and cetuximab synergistically induces an antiproliferative effect by triggering apoptosis and autophagy-dependent ferroptosis, both in vitro and in vivo