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Targeting p53 in vivo : a first-in-human study with p53-targeting compound APR-246 in refractory hematologic malignancies and prostate cancer

2000, Yudkoff et al

The challenge often lies in balancing antitumor efficacy with patient safety, a compromise that frequently leads to the development of drug resistance in patients [5]

Thus, 400 mg of glutathione is sufficient for skin whitening and healthier skin maintenance
