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Furthermore, this disruptive feature might be facilitated by the aggregation-promoting prion-like feature of FUS/TLS 52

doi: 10.1111/j.1549-8719.2000.tb00117.x 258 PfafflM

miR-223 deficiency increases eosinophil progenitor proliferation

Significantly, Parkinsons disease clinical manifestations are apparent only when there has been a substantial loss of dopaminergic neurons, typically 50%60%
