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2021;372:eaba2374

Jain N, Keating M, Thompson P, Ferrajoli A, Burger J, Borthakur G , Takahashi K, Estrov Z, Fowler N, Kadia T, Konopleva M, Alvarado Y, Yilmaz M, DiNardo C, Bose P, Ohanian M, Pemmaraju N, Jabbour E, Sasaki K, Kanagal-Shamanna R, Patel K, Jorgensen J, Garg N, Wang X, Sondermann K, Cruz N, Wei C, Ayala A, Plunkett W, Kantarjian H, Gandhi V, Wierda W

SMILES mediated input for the test compounds Structures of the test molecules are presented as a simplified molecular-input line entry system (SMILES) which were used for toxicity predictions

Description of two cohorts and criteria The study included two cohorts, each consisting of relatively equal groups of female patients, a cohort of lipedema patients and a healthy control group