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At spines, NMDARs mediate the induction of synaptic plasticity and NMDAR activation induces increases in the number of pre- and postsynaptic adapter protein nanomodules that underlie structural plasticity 25

Side effects are usually mild but can include temporary discomfort at the injection site, redness, or slight swelling

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To clarify gut microbiota interventions' efficacy in alleviating depressive symptoms, researchers did systematic reviews and meta-analyses, including RCT on probiotics, prebiotics, synbiotics or fecal microbiota transplantation in adults (18 years) that used validated, placebo-controlled measures to assess depressive symptoms
