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The adenosine binding pocket is strikingly similar, with the ribose moiety stacking with the conserved Trp61 residue and forming a network of polar interactions linking across the dimer interface via the conserved Glu71-His72 motif (Figs
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Similar to the anti-estrogenic group, only three AIs banned by WADA were identified in this study: letrozole, anastrozole, and exemestane
