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Isoliquiritigenin inhibits gastric cancer growth through suppressing GLUT4 mediated glucose uptake and inducing PDHK1/PGC-1 mediated energy metabolic collapse

Indeed, they also examine the role of CRMs in cellular processes such as autophagy, mitochondrial function, and cellular senescence, supporting the significant potential of pharmacological induction of autophagy as a viable and efficient strategy also against metabolic disorders

Palmer TD, Willhoite AR, Gage FH

for example, hawthorn leaf flavonoids have been shown to exert neuroprotective effects in an AD model by activating the Nrf2/ARE pathway, enhancing antioxidant enzyme activities, and reducing oxidative stress and neuroinflammation (Xu et al., 2023)