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Description
Unfortunately, characterization of disease severity in patients included in several studies in this review is scarce, and survival time is only accounted for in two trials [14,33]

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Takahashi A

Standard L-carnitine does not cross the blood-brain barrier efficiently and cannot contribute to acetylcholine synthesis

The enzyme acyl-CoA synthase converts long chain fatty acids to fatty acyl-CoAs, which are subsequently converted to acylcarnitines by the enzyme carnitine palmitoyltransferase I (CPT I) localized in the outer mitochondrial membrane [1, 43]
