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Description
Despite advancements, unanswered questions persist regarding GSH-degrading enzymes
153,154 Under conditions of insufficient glycolysis caused by glucose deprivation, 2-deoxyglucose treatment or Akt signaling inhibition, glutamine-addicted cells are more sensitive to GDH1 deficiency
How is it Used
Similarly, inhibition of ER stress by treatment with 4-phenylbutyric acid reduced cigarette smoke-induced inflammatory response, alveolar cell apoptosis, and airspace enlargement in mice (47)
