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How to Choose the Best Supplements for Erectile Dysfunction

The free radical hypothesis, proposed by Harman in 1956, [26] suggests that endogenous free radicals cause cumulative macromolecular damage, leading to aging and reduced physiological function [27]

The aging process is marked by a persistent dysregulation between pro-oxidant and antioxidant mechanisms, resulting in the excessive production of ROS that hinder eNOS functionality, diminish NO bioavailability, and exacerbate endothelial dysfunction (19)

[DOI] [PubMed] [Google Scholar] 77.Chen J., Chen S., Zhang B., Liu J