how does glutathione-s-transferase cause drug resistance in cancer cells Chemotherapy of Ovarian Frontiers | Iron-fueled ferroptosis: a
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It upregulates the expression of various genes involved in iron and ROS metabolism, such as NQO1, HO1, and FTH1, through the p62-Keap1-NRF2 pathway, inhibiting cellular ferroptosis [62]
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