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Description
PD is characterised by a progressive loss of, primarily, dopaminergic neurons of the substantia nigra that project to the striatum, resulting in its motor symptoms of bradykinesia, rigidity and tremor

The Phase 2 trial tested four dose levels, and the dose-response curve was remarkably linear
[DOI] [PMC free article] [PubMed] [Google Scholar] 253.Vega-Glvez A., Miranda M., Vergara J., Uribe E., Puente L., Martnez E.A

Hepatology , (2020)
