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Furthermore, the inhibition of angiogenesis mediated by GC not only directly reduces local blood supply within bone tissue but may also lead to a hypercoagulable state and enhance peripheral tissue vasoconstriction, which are high-risk factors for the development of ONFH 40

Using both oral and topical glutathione produced better results than either method alone

While not yet tested specifically in Lyme patients, studies demonstrate its influence on inflammatory pathways and immune cell signaling

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