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Description
Acetyl-L-carnitine Acetyl-L-carnitine (ALCAR) is available without a prescription as a nutritional supplement

We conducted an initial review via Google Scholar and PubMed and screened the available titles and abstracts

However, oral LC supplementation increases the levels of trimethylamine- N -oxide (TMAO) [12], which, as a pro-atherogenic factor, has been indicated to increase the risk of cardiovascular disease (CVD) [13], chronic kidney disease (CKD) [14], and even cancer [15]

End-stage renal disease L-Carnitine and short/medium-chain acylcarnitine molecules are removed from the circulation during hemodialysis
